Molecular Therapy: Methods & Clinical Development Vol. 18 September 2020 ª 2020 Authors from the Ocular Genomics Institute and Grousebeck Gene therapy Center have published the first proof of concept for a therapy to treat patients with NMNAT1-associated disease. No treatment is available for nicotinamide mononucleotide... Read More

Janey L. Wiggs (Mass Eye and Ear) has been selected by the Association for Research in Vision and Ophthalmology (ARVO) to receive the 2022 Mildred Weisenfeld Award for Excellence in Ophthalmology in recognition of her distinguished scholarly contributions to the clinical practice of ophthalmology. This award was established as a tribute to... Read More

Massachusetts Eye and Ear, a member hospital of Mass General Brigham, is entering into an exclusive licensing agreement with Biogen to develop a potential treatment for inherited retinal degeneration due to mutations in the PRPF31 gene, which are among the most common causes for autosomal dominant retinitis pigmentosa. Inherited retinal... Read More

Kinga M. Bujakowska, PhD, a molecular geneticist and Assistant Professor of Ophthalmology at Harvard Medical School, has been awarded the Research to Prevent Blindness 2020 RPB International Research... Read More

New research led by Drs. Janey Wiggs and Milica Margeta (Mass. Eye and Ear), recently published in Read More

Mass. Eye and Ear postdoctoral research fellow Caitlin Collin, PhD, was awarded a Career Starter Grant from the Knights Templar Eye Foundation. The grant will provide $70,000 of support for Dr. Collin’s research on the development of gene editing approaches for ABCA4-associated Stargardt disease. The Knights... Read More

Luk Vandenberghe PhD, Assistant Director of the Ocular Genomics Institute, Director of the Grousbeck Gene Therapy Center at Massachusetts Eye and Ear, and Associate Professor of Ophthalmology at Harvard Medical School is leading the work at Massachusetts Eye and Ear and Massachusetts General Hospital in the development of an experimental... Read More

AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE... Read More

Dr. Ayellet Segrè is part of a team of investigators awarded a $2 million grant by the Chan Zuckerberg Initiativeto build a cell atlas of the human eye from birth to old age, as part of a global research effort called the Human Cell Atlas,using single cell RNA-sequencing, and to identify gene expression and regulation specific to different cell... Read More

On July 10th staff from all the OGI labs gathered for a scavenger hunt in Kendall Square followed by lunch at Flat Top Johnny’s.  Thanks to all who turned out to make this a fun event.    Congratulations to Team 3 for winning the scavenger hunt!   Here are the photos uploaded during... Read More