CRISPR Gene Editing shown to be effective in improving vision
May 20, 2024Boston, Mass. — Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated. The phase 1/2 trial called BRILLIANCE, was led by principal investigator Read More
Knights Templar Eye Foundation 2024- 2025 Career Starter Grants
May 2, 2024Ocular Genomics Institute members Hanmeng Zhang, Egle Galdikatie-Braziene, and Kannan Manian were awarded support for their work. Hanmeng Zhang, PhD: Investigating the role of Oxidative DNA... Read More
Dr. Ryoji Amamoto receives Child Health Research Grant Award from the Charles H. Hood foundation.
January 29, 2024Ryoji Amamoto, PhD, an Assistant Scientist in the Department of Ophthalmology, has been selectedto receive a Child Health Research Grant Award fromthe Charles H. Hood Foundation. These highly competitive awards provide $200,000 over two years to support scientific research and advance the careers of promising scientists at premier New... Read More
Inas Aboobakar, M.D – K23 clinician-scientist grant recipient.
January 29, 2024Dr. Inas Aboobakar of the Wiggs lab received a K23 clinician-scientist grant from the National Eye Institute. With this grant, Dr. Aboobakar will investigate the clinical impact and underlying disease mechanisms for glaucoma-associated genes that function in the mitochondria, the energy-producing parts of cells. This work is designed to help pave... Read More
Research to Prevent Blindness/The Glaucoma Foundation 2023 Career Advancement Award
January 29, 2024Ayellet Segrè, PhD, an Assistant Professor of Ophthalmology at Mass Eye and Ear, Harvard Medical School, received the Research to Prevent Blindness/The Glaucoma Foundation 2023 Career Advancement Award. Dr. Segrè will use this award to identify genetic regulatory effects at the single cell level in the aqueous humor outflow pathways, retina,... Read More
Shedding light on glaucoma causal mechanisms, genes and cell types
January 29, 2024Ayellet Segrè, PhD, an Assistant Professor of Ophthalmology at Harvard Medical School, and Genetic Biostatistician at the Ocular Genomics Institute at Mass. Eye and Ear (MEE), and her lab members, in collaboration with Janey Wiggs, MD, Ph.D., Ocular Genomics Institute Associate Director, and Professor of Ophthalmology at HMS, Josh Sanes,... Read More
Elizabeth Rossin – 2024 Glaser Award recipient
January 23, 2024The Association for Research in Vision and Ophthalmology (ARVO) Foundation congratulates Elizabeth Rossin, MD, PhD — 2024 recipient of the Bert M. Glaser, MD Award for Innovative Research in Retina. The award recognizes an early-career investigator who has discovered a novel drug, technique, or the understanding of a mechanism of disease... Read More
Ayellet Segrè Receives RPB/Glaucoma Foundation Career Advancement Award
January 23, 2024Ayellet Segrè (Mass Eye and Ear) has been recognized with the Research to Prevent Blindness (RPB)/Glaucoma Foundation Career Advancement Award. Hundreds of common DNA variants have been found to be associated with primary open-angle glaucoma (POAG). The majority of these variants lie in noncoding regions and likely affect glaucoma through... Read More
Drs. Bujakowska and Comander awarded Massachusetts Lions Eye Research Fund grants
January 9, 2024Two members of the Ocular Genomics Insitute are among 6 researchers receiving funding for their innovative research projects during the 2023=2024 academic year. Kinga Bujakowska, PhD will study “ Development of long-read sequencing approaches for genetic diagnosis of... Read More
Retreat 2023
October 12, 2023The 2023 Ocular Genomics Institute Scientific Retreat took place on Wednesday September 27th at the Museum of Science. Almost 80 OGI members from all our labs participated. With 11 presentations and 20 posters it was a full day of science and a great opportunity to renew relationships and to foster new relationships and... Read More
OGI iPS Special Seminar
May 31, 20233D Human organoids are a major technological breakthrough that has shaped the landscape of disease modeling, gene, and cell therapies in recent years. The Ocular Genomics Institute of the Massachusetts Eye and Ear of Harvard Medical School is thrilled to organize a special seminar with this exceptional panel of experts on human tissue models for... Read More